Ketamine is a well researched anesthetic agent that has been used safely and effectively to treat a variety of mental health and physical medical conditions. I work with my team at Your Wellness Practice to provide ketamine infusions in the comfort and safety of my office. We provide infusions for treatment-resistant Major Depressive Disorder, depressive phases of Bipolar Disorder, suicidality, severe anxiety disorders, OCD, and PTSD. We have seen rapid and significant benefit, consistent with published studies on ketamine for this use [1-5].
Ketamine can open the possibility of symptom relief and solidifying new patterns of thinking, feeling, and responding to daily stressors through multiple effects on the brain. By blocking receptors for glutamate, the most prevalent excitatory signaling chemical in the brain, we observe a subsequent increase in release of glutamate into the space between cells. This has a cascade of effects and ultimately triggers release of brain derived neurotrophic factor or BDNF. BDNF is a key player in neuroplasticity, which helps to restore normal connectivity between key brain regions. The activity of the Default Mode Network (DMN) also dampens and diminishes, which can be felt as a lessening of obsessive and negative thinking. As old stuck patterns begin to loosen up, and new connections form, the brain has the opportunity to transform over time into a healthier baseline state of being.
Ketamine provides a novel biological approach to treat some of the most refractory and debilitating mental health symptoms, and effects are rapid and robust.
How Do I Know Whether Ketamine Infusions or Ketamine-Assisted Psychotherapy Are Right For Me?
Ketamine Infusions might be right for you if:
You are focused on rapid relief of moderate to severe symptoms.
You are seeking to avoid a higher level of care, such as hospitalization.
You are experiencing suicidal thoughts.
Learn more about ketamine infusions, or reach out to schedule here.
Ketamine-Assisted Psychotherapy might be right for you if:
You are working on understanding and unwinding stuck patterns in your life and relationships.
You are feeling blocked in therapy and wish to access more of your own consciousness.
Your symptoms are controlled enough so that you have the time to devote to creating a solid therapeutic container for this process.
Learn more about ketamine-assisted psychotherapy here.
1. Zarate CA, et al. A randomized trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression. Arch Gen Psychiatry. 2006 Aug; 63(8): 856-64.
2. DiazGranados N, et al. Rapid Resolution of Suicidal Ideation After a Single Infusion of an N-methyl-D-aspartate Antagonist in Patients with Treatment-Resistant Major Depressive Disorder. J. Clin. Psychiatry. 2010 Dec; 71(12): 1605-11.
3. DiazGranados N, Ibrahim L, Brutsche NE, et al. A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression. ArchGen Psychiatry. 2010; 67(8): 793–802.
4. Glue, P, Neehoff, SM, Medlicott, NJ, Gray, A, Kibby, G, & McNaughton, N (2018). Safety and Efficacy of Maintenance Ketamine Treatment in Patients with Treatment-Refractory Generalised Anxiety and Social Anxiety Disorders. Journal of Psychopharmacology, 32(6), 663–667.
5. Feder A, Parides MK, Murrough JW, et al. Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2014; 71(6): 681–688.